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Phenylpiracetam Hydrazide

$39.99

Phenylpiracetam, also known as phenotropil, is a popular synthetic nootropic compound renowned for its cognitive-enhancing properties. Originally developed in Russia in the 1980s, phenylpiracetam belongs to the racetam family and is celebrated for its potential to boost mental performance, focus, and productivity.  
Chemical Formula  C12H14N2O2
Synonyms  Phenotropil; Carphedon
IUPAC Name  (R,S)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide
Molar mass  218.256 g·mol−1
Elimination half-life  3-5 Hours
Melting Point  486.4 °C
Purity  ≥99.9%
Appearance  White crystalline solid powder
Storage  Store in a dry environment at Room Temperature
Terms  All products are for laboratory developmental research USE ONLY. Products are not for human consumption.

Disclaimer: Legal Status and Usage Advisory for Phenylpiracetam

Phenylpiracetam, also known as Phenotropil, is not prescribed as a pharmaceutical in Western countries.  However, it was available as a prescription medicine in Russia under the name Phenotropil until April 2017  when it was discontinued due to licensing issues. It is essential to note that Phenylpiracetam is not scheduled by the U.S. Drug Enforcement Administration (DEA), indicating its legal status in the United States.

What is Phenylpiracetam?

Phenylpiracetam is a nootropic compound that has been extensively studied in laboratory research and animal studies. Derived from the racetam family, it is known for its cognitive-enhancing properties. In lab research, Phenylpiracetam has shown potential in improving memory, learning, and cognitive functions.  Animal studies suggest that it may positively influence neurotransmitter systems, particularly involving acetylcholine and glutamate, contributing to its cognitive effects. While further research is needed, these findings indicate that Phenylpiracetam holds promise as a nootropic compound with potential cognitive benefits [1]. 

What is the Chemistry of Phenylpiracetam?

The chemistry of Phenylpiracetam, also known as phenotropil, is characterized by its molecular structure and formula, C12H14N2O2. This compound is a member of the racetam family, a class of nootropic substances known for their cognitive-enhancing effects. Phenylpiracetam is derived from piracetam, with the addition of a phenyl group to its molecular structure. This modification increases its bioavailability and potency by enabling it to cross the blood-brain barrier more effectively. The molecular structure of Phenylpiracetam allows it to interact with various neurotransmitter systems in the brain, including acetylcholine and glutamate, which are involved in learning and memory processes. These chemical properties contribute to Phenylpiracetam’s reputation as a potent cognitive enhancer [2].

What is the Mechanism of Action of Phenylpiracetam?

Phenylpiracetam’s mechanism of action centres around its influence on neurotransmitter systems within the brain. Acting as a positive modulator, it interacts with receptors for acetylcholine—a neurotransmitter crucial for cognitive functions such as memory and learning. Additionally, Phenylpiracetam appears to impact glutamate receptors, further contributing to its cognitive effects. The exact details of how these  interactions occur are not fully understood. Still, the enhancement of cholinergic and glutamatergic signalling is believed to play a role in the observed cognitive benefits. This multifaceted modulation of neurotransmitter activity underscores Phenylpiracetam’s reputation as a nootropic with potential cognitive-enhancing properties in animals [3]. 

What are the Diverse Forms of Phenylpiracetam?

Phenylpiracetam is commonly available in different forms to cater to varied preferences. The most common forms include: 

Phenylpiracetam Powder

In laboratory research, Phenylpiracetam powder stands out as a versatile and preferred form due to its precise dosing capabilities. Researchers utilize the powder to ensure accurate measurements, allowing for meticulous control over dosage levels in studies investigating the compound. 

Laboratory Research

  • Precise Dosage Control: Phenylpiracetam powder enables researchers to accurately measure doses, ensuring consistency and reliability in experimental outcomes. 
  • Versatility: The powder form offers flexibility in experimental design, allowing for easy adjustment of dosage levels.
  • Cost-Effectiveness: In laboratory settings, Phenylpiracetam powder often provides a more economical option compared to other forms, making it a preferred choice for researchers aiming to maximize resources without compromising research quality.
Phenylpiracetam Hydrazide is a modified version of the nootropic substance called  Phenylpiracetam. In simple terms, it’s a variation created by adding a hydrazide group to  Phenylpiracetam’s structure. This modification alters how the compound behaves. It is known for its potential to boost cognitive functions like focus and memory. Phenylpiracetam Hydrazide, being a newer form, might have its unique effects, but research on it is limited. [5].  Future Research and Clinical Trials   While these findings are encouraging, additional research, including clinical trials, is essential to comprehensively understand the extent of Phenylpiracetam’s benefits and its potential applications [1].  Phenylpiracetam, a nootropic substance gaining popularity for its cognitive-enhancing effects, operates by influencing various neurotransmitters and brain functions. Its mechanisms of action, as suggested by research and laboratory studies, involve several cognitive and neural pathways: 

Cholinergic System Modulation

Studies indicate that Phenylpiracetam may modulate the cholinergic system, enhancing the activity of acetylcholine. This neurotransmitter is crucial for memory and cognitive functions. Dopaminergic Enhancement Laboratory research suggests that Phenylpiracetam might influence dopamine receptors, leading to increased dopamine levels. This neurotransmitter is associated with mood, motivation, and cognitive processes.  Nootropic Effects   In animal models, Phenylpiracetam has shown potential nootropic effects, enhancing cognitive functions such as memory, learning, and attention.  Neuroprotective Properties   Research in laboratory settings proposes that Phenylpiracetam may have neuroprotective properties, safeguarding neurons from damage or degeneration.  Enhanced Physical Performance   Some research suggests that Phenylpiracetam may positively influence physical performance, making it a compound studied not only for cognitive benefits but also for potential ergogenic effects.  Understanding these mechanisms in the context of research and laboratory studies contributes to our knowledge of Phenylpiracetam’s potential cognitive-enhancing properties. It’s important to note that further research is needed to fully elucidate its effects and mechanisms. [6]. 

Piracetam vs Phenylpiracetam?

When delving into the world of nootropics, the choice between Piracetam and Phenylpiracetam often arises. These cognitive enhancers belong to the racetam family, but they exhibit distinct characteristics.  Let’s unravel the differences between Piracetam and Phenylpiracetam:  Basic Mechanism  
  1.  Piracetam: Known as the pioneering racetam, Piracetam influences acetylcholine receptors, enhancing cholinergic neurotransmission.  
  2. Phenylpiracetam: With an added phenyl group, Phenylpiracetam is structurally different from Piracetam. It acts on acetylcholine and dopamine receptors. 

References

    1. Malykh, A. G., & Sadaie, M. R. (2010). Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs, 70, 287-312. 
    2. Zvejniece, L., Svalbe, B., Veinberg, G., Grinberga, S., Vorona, M., Kalvinsh, I., & Dambrova, M. (2011).  Investigation into the stereoselective pharmacological activity of phenotropil. Basic & clinical pharmacology & toxicology, 109(5), 407-412. 
    3. Grebeniuk, O. V., Zhukova, N. G., & Alifirova, V. M. (2014). The efficacy of add-on treatment with phenotropil in adult patients with locally induced epilepsy. Zhurnal nevrologii i psikhiatrii imeni SS  Korsakova, 114(11 Pt 2), 27-31. 
    4. Tardner, P. (2022). Does Phenylpiracetam Increase Dopamine? 
    5. Wang, P. L., Chan, Y. X., & Chang, C. C. (2023). New synthesis of β-aryl-GABA drugs. Tetrahedron, 146,  133648. 
    6. Firstova, Y. Y., Abaimov, D. A., Kapitsa, I. G., Voronina, T. A., & Kovalev, G. I. (2011). The effects of scopolamine and the nootropic drug phenotropil on rat brain neurotransmitter receptors during testing of the conditioned passive avoidance task. Neurochemical Journal, 5, 115-125. 
    7. Cohen, P. A., Avula, B., Wang, Y. H., Zakharevich, I., & Khan, I. (2021). Five unapproved drugs found in cognitive enhancement supplements. Neurology: Clinical Practice, 11(3), e303-e307. 8. Tardner, P. (2021). Piracetam vs Phenylpiracetam.

Disclaimer

The statements made within this website have not been evaluated by the U.S. Food and Drug Administration. These statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease. All products are for RESEARCH PURPOSES ONLY. All information contained on this website is for educational purposes.
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